Literatur-DB: Newcastle disease virus triggers autophagy in U251 glioma cells to enhance virus replication.
| Titel: | Newcastle disease virus triggers autophagy in U251 glioma cells to enhance virus replication. |
| Kategorien: | Glioblastom |
| BuchID: | 43 |
| Autor: | Verschiedene |
| ISBN-10(13): | KA |
| Publikationsdatum: | 2012 06 |
| Number of pages: | 0 |
| Sprache: | Nicht spezifiziert |
| Preis: | 0.00 |
| Bewertung: |
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| Beschreibung: |
AbstractNewcastle disease virus (NDV) can replicate in tumor cells and induce apoptosis in late stages of infection. However, the interaction between NDV and cells in early stages of infection is not well understood. Here, we report that, shortly after infection, NDV triggers the formation of autophagosomes in U251 glioma cells, as demonstrated by an increased number of double-membrane vesicles, GFP-microtubule-associated protein 1 light chain 3 (GFP-LC3) a dot formations, and elevated production of LC3II. Artikel-Nr.: 157(6):1011-8 | PubMed-ID: 22398914 | DOI: 10.1007/s00705-012-1270-6 | ISBN: |
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