Literatur-DB: Immunological response after WT1 mRNA-loaded dendritic cell immunotherapy in ovarian carcinoma and carcinosarcoma.
 
Titel:      Immunological response after WT1 mRNA-loaded dendritic cell immunotherapy in ovarian carcinoma and carcinosarcoma.
Kategorien:      Dendritische Zellen
BuchID:      17
Autor:      Verschiedene
ISBN-10(13):      KA
Publikationsdatum:      2013 09
Number of pages:      0
Sprache:      Nicht spezifiziert
Preis:      0.00
Bewertung:      0 
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Beschreibung:     

Abstract

BACKGROUND:

Dendritic cell (DC)-based immunotherapy is an emerging new treatment option in ovarian cancer, an important cause of cancer-related mortality.

PATIENTS AND METHODS:

One patient with ovarian carcinosarcoma (OCS) and one with serous ovarian cancer (SOC) received four weekly vaccinations of autologous DCs electroporated with mRNA coding for the Wilms' tumor gene 1 (WT1). Safety, feasibility and immunogenicity were assessed.

Artikel-Nr.: 33(9):3855-9 | PubMed-ID: 24023319 | DOI: | ISBN:


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