Literatur-DB: Monocyte-derived dendritic cells from HCV-infected patients transduced with an adenovirus expressing NS3 are functional when stimulated with the TLR3 ligand poly(I:C).
 
Titel:      Monocyte-derived dendritic cells from HCV-infected patients transduced with an adenovirus expressing NS3 are functional when stimulated with the TLR3 ligand poly(I:C).
Kategorien:      Chronische Virushepatitis
BuchID:      102
Autor:      Verschiedene
ISBN-10(13):      KA
Publikationsdatum:      2008 11
Number of pages:      0
Sprache:      Nicht spezifiziert
Preis:      0.00
Bewertung:      0 
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Beschreibung:     

Abstract

Dendritic cells (DC) transfected with an adenovirus encoding hepatitis C virus (HCV) NS3 protein (AdNS3) induce potent antiviral immune responses when used to immunize mice. However, in HCV infected patients, controversial results have been reported regarding the functional properties of monocyte-derived DC (MoDC), a cell population commonly used in DC vaccination protocols.

Artikel-Nr.: 15(11):782-9 | PubMed-ID: 18637068 | DOI: 10.1111/j.1365-2893.2008.01020.x | ISBN:


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