Literatur-DB: Engineered newcastle disease virus as an improved oncolytic agent against hepatocellular carcinoma.
| Titel: | Engineered newcastle disease virus as an improved oncolytic agent against hepatocellular carcinoma. |
| Kategorien: | Hepatozelluläres Karzinom |
| BuchID: | 80 |
| Autor: | Verschiedene |
| ISBN-10(13): | KA |
| Publikationsdatum: | 2010 02 |
| Number of pages: | 0 |
| Sprache: | Nicht spezifiziert |
| Preis: | 0.00 |
| Bewertung: |
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| Bild: |
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| Beschreibung: |
AbstractNewcastle disease virus (NDV) is an intrinsically tumor-specific virus, which is currently under investigation as a clinical oncolytic agent. Several clinical trials have reported NDV to be a safe and effective agent for cancer therapy; however, there remains a clear need for improvement in therapeutic outcome. The endogenous NDV fusion (F) protein directs membrane fusion, which is required for virus entry and cell-cell fusion. Artikel-Nr.: 18(2):275-84 | PubMed-ID: 19809404 | DOI: 10.1038/mt.2009.231 | ISBN: |
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