Literatur-DB: Production of a dendritic cell-based vaccine containing inactivated autologous virus for therapy of patients with chronic human immunodeficiency virus type 1 infection.
 
Titel:      Production of a dendritic cell-based vaccine containing inactivated autologous virus for therapy of patients with chronic human immunodeficiency virus type 1 infection.
Kategorien:      HIV/AIDS
BuchID:      93
Autor:      Verschiedene
ISBN-10(13):      KA
Publikationsdatum:      2009 02
Number of pages:      0
Sprache:      Nicht spezifiziert
Preis:      0.00
Bewertung:      0 
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Beschreibung:     

Abstract

In preparation for a pilot clinical trial in patients with chronic human immunodeficiency virus type 1 (HIV-1) infection, a novel dendritic cell (DC)-based vaccine is being manufactured. The trial will test the hypothesis that isolated endogenous virus presented by DCs serves as a potent immunogen for activation of CD8(+) and CD4(+) T cells specific for a broad range of autologous HIV-1 antigens.

Artikel-Nr.: 16(2):233-40 | PubMed-ID: 19038780 | DOI: 10.1128/CVI.00066-08 | ISBN:


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