Literatur-DB: Immunological response after WT1 mRNA-loaded dendritic cell immunotherapy in ovarian carcinoma and carcinosarcoma.
Titel: | Immunological response after WT1 mRNA-loaded dendritic cell immunotherapy in ovarian carcinoma and carcinosarcoma. |
Kategorien: | Dendritische Zellen |
BuchID: | 17 |
Autor: | Verschiedene |
ISBN-10(13): | KA |
Publikationsdatum: | 2013 09 |
Number of pages: | 0 |
Sprache: | Nicht spezifiziert |
Preis: | 0.00 |
Bewertung: | |
Bild: | zum Original |
Beschreibung: |
AbstractBACKGROUND:Dendritic cell (DC)-based immunotherapy is an emerging new treatment option in ovarian cancer, an important cause of cancer-related mortality. PATIENTS AND METHODS:One patient with ovarian carcinosarcoma (OCS) and one with serous ovarian cancer (SOC) received four weekly vaccinations of autologous DCs electroporated with mRNA coding for the Wilms' tumor gene 1 (WT1). Safety, feasibility and immunogenicity were assessed. Artikel-Nr.: 33(9):3855-9 | PubMed-ID: 24023319 | DOI: | ISBN: |
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