Literatur-DB: Monocyte-derived dendritic cells from HIV type 1-infected individuals show reduced ability to stimulate T cells and have altered production of interleukin (IL)-12 and IL-10.
 
Titel:      Monocyte-derived dendritic cells from HIV type 1-infected individuals show reduced ability to stimulate T cells and have altered production of interleukin (IL)-12 and IL-10.
Kategorien:      HIV/AIDS
BuchID:      88
Autor:      Verschiedene
ISBN-10(13):      KA
Publikationsdatum:      2009 06
Number of pages:      0
Sprache:      Nicht spezifiziert
Preis:      0.00
Bewertung:      0 
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Beschreibung:     

Abstract

Monocyte-derived dendritic cells (MDDCs) have been used in therapeutic vaccination for cancer. A small number of studies have employed a similar approach to vaccinate human immunodeficiency virus (HIV)-infected individuals. We have thus analyzed the functional properties of MDDCs generated from HIV-infected individuals who either are receiving highly active antiretroviral therapy or are therapy naive. There was no difference in the MDDC phenotype or efficiency of MDDC generation between HIV-infected individuals and healthy control subjects.

Artikel-Nr.: 199(12):1862-71 | PubMed-ID: 19419334 | DOI: 10.1086/599122 | ISBN:


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